Flunitrazepam Flunitrazepam structure

Flunitrazepam
Flunitrazepam structure.svg
Flunitrazepam-from-xtal-3D-balls.png
Clinical data
Pronunciation /?flu?n??træz?pæm/
Trade names Rohypnol
Pregnancy
category
AU: C
Dependence
liability Very high
Routes of
administration Oral (tablets)
ATC code
N05CD03 (WHO)
Legal status
Legal status
AU: S8 (Controlled)
CA: Schedule I
DE: Anlage III (Special prescription form required)
UK: Class C
US: Schedule IV
Sweden schedule II

UN: Psychotropic Schedule III
Pharmacokinetic data
Bioavailability 64–77% (oral)
50% (suppository)
Metabolism Hepatic
Elimination half-life 18–26 hours
Excretion Renal
Identifiers
IUPAC nameshow
CAS Number
1622-62-4 Yes
PubChem CID
3380
IUPHAR/BPS
4193
DrugBank
DB01544 Yes
ChemSpider
3263 Yes
UNII
620X0222FQ
KEGG
D01230 Yes
ChEMBL
CHEMBL13280 Yes
ECHA InfoCard 100.015.089 Edit this at Wikidata
Chemical and physical data
Formula C16H12FN3O3
Molar mass 313.3 g/mol
3D model (JSmol)
Interactive image
SMILESshow
InChIshow
(verify)
Flunitrazepam, also known as Rohypnol among other names,1 is an intermediate acting benzodiazepine used in some countries to treat severe insomnia and in fewer, early in anesthesia.2

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Just as with other hypnotics, flunitrazepam should be strictly used only on a short-term basis or by those with chronic insomnia on an occasional basis.2 Flunitrazepam has been referred to as a date rape drug even though its incidence is very rare in reported rape cases.3